(A) a plurality of granules comprising a pharmaceutically active compound, one or more amino acids selected from the group consisting of glycine, alanine, valine, leucine, iso-leucine, phenylalanine, proline, aspartic acid, glutamic acid, lysine, arginine, histidine, serine, threonine, cysteine, asparagine and glutamine, and an intragranular polymer; and,

(B) a hydrophilic extragranular polymer in which said granules are dispersed, said extragranular polymer being more rapidly hydrating than said intragranular polymer, wherein:

the amino acid is selected for hydropathy characteristics depending on solubility characteristics of the active compound, and

when said active compound is sparingly or more than sparingly soluble in water, said amino acid has a relatively equal balance between hydrophobic and hydrophilic components or is relatively more hydrophilic; and

when said active compound is less than sparingly soluble in water, said amino acid is a combination of at least two amino acids, one of which is moderately or strongly hydrophobic, the other of which is relatively more hydrophilic.