|
| Issue 1299-4 |
| US 6,958,152 B2 |
| Human phospholipase C delta 5 |
| Klaus Dücker, Darmstadt (Germany); Silke Brandt, Darmstadt (Germany); and Johannes Gleitz, Darmstadt (Germany) |
| Assigned to Merck Patent GmbH, Darmstadt (Germany) |
| Appl. No. 10/258,860 PCT Filed Apr. 27, 2001, PCT No. PCT/EP01/04784 § 371(c)(1), (2), (4) Date Oct. 29, 2002, PCT Pub. No. WO01/83771, PCT Pub. Date Nov. 08, 2001. |
| Claims priority of application No. 00109318 (EP), filed on Apr. 29, 2000. |
| Prior Publication US 2003/0100039 A1, May 29, 2003 |
| Int. Cl.7A61K 39/00 |
| U.S. Cl. 424—192.1 [435/198; 435/252.3; 435/320.1; 536/23.2] | 4 Claims |
| 1. An isolated polypeptide having phospholipase C delta 5 activity, selected from a group consisting of:
(a) a polypeptide encoded by a polynucleotide comprising the sequence of SEQ ID NO: 3;
(b) a polypeptide comprising a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID NO:
4;
(c) a polypeptide consisting of a polypeptide sequence having at least 95% identity to the polypeptide sequence of SEQ ID
NO: 4;
(d) a polypeptide sequence of SEQ ID NO: 4; and
(e) a fragment of the polypeptides in (a) to (d), having phospholipase C delta 5 activity.
|